Herpes
Chemical properties, mode of action, and in vivo anti-herpes activities of a lignin-carbohydrate complex from Prunella vulgaris
In conclusion, the anti-HSV compound from P. vulgaris is a
lignin-polysaccharide complex with potent activity against HSV-1 and
HSV-2. Its mode of action appears to be inhibiting viral binding and
penetration into host cells.
Medicinal herb Prunella vulgaris, Xia Ku Cao, downregulates the expression of herpes simplex virus
Results from this study show that PPV is effective against both the
HSV-1 and HSV-2 infections, and flow cytometry offers a quantitative
and highly reproducible anti-HSV drug-susceptibility assay.
Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients
CONCLUSION(S): The DNA of STI pathogens was detected in semen from a
high percentage of asymptomatic male infertility patients, and was
associated with poor semen quality. Efforts to diagnose and treat
subclinical genital-tract infections should be intensified.
Asymptomatic genital herpes infection and infertility in males
Thus, asymptomatic HSV infection has a negative effect on male fertility.
Herpetic infection of spermatozoa in failure of reproductive technologies and spontaneous abortion
The following conclusions can be made: mobile spermatozoa of normal
morphology can be infected with HSV; as shown morphologically, samples
of ejaculate from men whose wives had spontaneous abortions contained
intragametic HSV capsides; intragametic HSV infection of spermatozoa
had a negative effect on the course of pregnancy and/or embryon
vitality.
Infection of cytomegalovirus and herpes simplex virus and morphology of the infected spermatogenic cells in infertile men
CONCLUSION: Spermatogenic cells infected by HCMV and HSV-II may cause
pathologic lesions and affect spermatogenesis. Morphologically, the
infected spermatogenic cells may undergo some pathologic alteration,
such as apoptosis. The rate of HCMV infection is higher among infertile
males with pathologic cells in the semen.
Prevalence of human herpes virus in the semen of men attending an infertility clinic and correlation with semen parameters
CONCLUSION(S): The DNA of herpes viruses is frequently detected in the
semen of asymptomatic fertile and infertile male patients. Further
studies are required to investigate the role of herpes viruses in male
factor infertility.
Altered immunophenotypic parameters in infertile women. Possible role of herpes viremia.
CONCLUSIONS: Assuming that all women under study remained asymptomatic,
these data suggest that subclinical herpesvirus viremia may be an
important cause of peripheral immunostimulation in women with a history
of infertility
Stress impairs the immune response to mucosal herpes simplex (HSV-1) infection.
We conclude that the increased viral titers observed in
mice experiencing psychological stress are the consequence of a
glucocorticoid-mediated reduction in the numbers of lymphocytes
responsible for resolving the initial infection.
Inhibitory activity of Lemon Balm (Melissa officinalis L.) extract on Herpes simplex virus type 2 replication.
Our experiments support the use of
lemon balm for treating Herpes simplex lesions and encourage clinical
trials on this medicinal plant.
