Acne is a common problem faced by many women in their reproductive years. Often times it indicates elevated androgens (male hormones) and may be associated with menstrual irregularities, and even Poly Cystic Ovarian Syndrome, a condition that involves two of the following criteria:

Hormonal Acne

When
pimples appear or increase on a woman's face as she approaches
menstruation, she is suffering with 'hormonal' or 'premenstrual' acne.
While some only get one or two pimples and don't find them much of a
burden, other women's acne can be deep, painful, and widespread,
covering their entire face, chest, and back. Besides the risk of
permanent scarring from picking pimples, the emotional stress
associated with their appearance tends to be the hardest on women.
Being more than skin deep, pimples that fluctuate with the menstrual
cycle signify an underlining hormonal imbalance and even problems
related to a women's fertility.

I recently found several research studies posted on the PubMed research data base that make direct parallels to Accutane use and ulcerative colitis.

Acne and stress have a synergistic relationship, meaning the
more stressed a person is the more acne they will develop and with more